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Peptide therapeutics are a class of medications derived from peptides—short chains of amino acids that mimic or influence natural biological processes. These drugs are increasingly gaining attention due to their high specificity, potency, and favorable safety profile. Peptide-based drugs can target a wide range of diseases, including cancer, metabolic disorders, cardiovascular conditions, and infectious diseases. They often interact with cell surface receptors or enzymes and are capable of modulating key signaling pathways. Because peptides are naturally occurring in the body, they are typically well tolerated and have lower toxicity compared to small-molecule drugs.
Despite their advantages, peptide therapeutics face challenges such as poor oral bioavailability, rapid degradation by enzymes, and short half-life in circulation. To overcome these limitations, advanced delivery methods like injectable formulations, nanoparticle encapsulation, and chemical modifications (e.g., PEGylation or cyclization) are being developed. The global peptide therapeutics market is expanding rapidly, driven by advancements in biotechnology and growing demand for targeted therapies. Drugs like insulin, glucagon-like peptide-1 (GLP-1) analogs, and cancer-targeting peptides exemplify the success of this category in clinical applications.
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